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Utilidad de probióticos y vitaminas en el tratamiento de dermatitis atópica en la población general
Resumen
La dermatitis atópica (EA) es una enfermedad crónica de la piel que afecta a un gran número de personas en todo el mundo. El uso de terapias complementarias como los probióticos y las vitaminas ha surgido como una alternativa prometedora para mejorar el manejo de esta enfermedad. El objetivo de este estudio es establecer la eficacia de los probióticos y las vitaminas en el tratamiento de la dermatitis atópica mediante la revisión bibliográfica en páginas indexadas. Se realizó una revisión documental exhaustiva utilizando la base de datos PubMed, centrándose en estudios de los últimos cinco años que cumplieran con criterios específicos de inclusión. Los hallazgos resaltaron la importancia de la microbiota intestinal en la salud dermatológica apoyada con la administración de probióticos, así como la evidencia creciente que respalda la eficacia de la suplementación con vitaminas, especialmente la vitamina D y E, en el tratamiento de la dermatitis atópica. Se subraya la relevancia de los enfoques terapéuticos complementarios en el manejo de la dermatitis atópica, abriendo nuevas oportunidades para mejorar los resultados de los pacientes y promoviendo una atención más integral y eficaz en su búsqueda de bienestar dermatológico.
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Referencias
Alam, M. J., Xie, L., Yap, Y. A., Marques, F. Z., & Robert, R. (2022). Manipulating Microbiota to Treat Atopic Dermatitis: Functions and Therapies. Pathogens, 11(6), 642. https://www.mdpi.com/2076-0817/11/6/642
Anania, C., Brindisi, G., Martinelli, I., Bonucci, E., D'Orsi, M., Ialongo, S., ... & Duse, M. (2022). Probiotics Function in Preventing Atopic Dermatitis in Children. International Journal of Molecular Sciences, 23(10), 5409. https://www.mdpi.com/1422-0067/23/10/5409
Bieber, T. (2022). Atopic dermatitis: an expanding therapeutic pipeline for a complex disease. Nature Reviews Drug Discovery, 21(1), 21-40. https://www.nature.com/articles/s41573-021-00266-6
Chu, D. K., Chu, A. W. L., Rayner, D. G., Guyatt, G. H., Yepes-Nuñez, J. J., Gomez-Escobar, L., ... & Thabane, L. (2023). Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials. Journal of Allergy and Clinical Immunology, 152(6), 1493-1519. https://www.jacionline.org/article/S0091-6749(23)01113-2/fulltext
Çiçek, F., & Köle, M. T. (2023). Evaluation of the Impact of Serum Vitamin D Levels on the Scoring Atopic Dermatitis Index in Pediatric Atopic Dermatitis. Children, 10(9), 1522. https://www.mdpi.com/2227-9067/10/9/1522
Colquitt, A. S., Miles, E. A., & Calder, P. C. (2022). Do Probiotics in Pregnancy Reduce Allergies and Asthma in Infancy and Childhood? A Systematic Review. Nutrients, 14(9), 1852. https://www.mdpi.com/2072-6643/14/9/1852
Delhomme, C., Adam, T., Seiller, H., & Bursztejn, A. C. (2024). Characteristics of atopic dermatitis patients using complementary and alternative medicine: A literature review. Annales de Dermatologie et de Vénéréologie, 151(1), 103257. https://www.sciencedirect.com/science/article/pii/S0151963824000139
Fanfaret, I. S., Boda, D., Ion, L. M., Hosseyni, D., Leru, P., Ali, S., ... & Costea, R. (2021). Probiotics and prebiotics in atopic dermatitis: Pros and cons (Review). Experimental and Therapeutic Medicine, 22(6), 1-8. https://www.spandidos-publications.com/10.3892/etm.2021.10811
Fang, Z., Li, L., Zhang, H., Zhao, J., Lu, W., & Chen, W. (2021). Gut Microbiota, Probiotics, and Their Interactions in Prevention and Treatment of Atopic Dermatitis: A Review. Frontiers in Immunology, 12, 720393. https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.720393/full
Fijan, S., Kolč, N., Hrašovec, M., Jamtvedt, G., Pogačar, M. Š., Mičetić Turk, D., ... & Tavzes, B. (2023). Single-Strain Probiotic Lactobacilli for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis. Pharmaceutics, 15(4), 1256. https://www.mdpi.com/1999-4923/15/4/1256
Frazier, W., & Bhardwaj, N. (2020). Atopic Dermatitis: Diagnosis and Treatment. American Family Physician, 101(10), 590-598. https://www.aafp.org/pubs/afp/issues/2020/0515/p590.html
Fu, H., Li, Y., Huang, H., & Wang, D. (2022). Serum Vitamin D Level and Efficacy of Vitamin D Supplementation in Children with Atopic Dermatitis: A Systematic Review and Meta-analysis. Computational and Mathematical Methods in Medicine, 2022, 9407888. https://onlinelibrary.wiley.com/doi/abs/10.1155/2022/9407888
Hattangdi-Haridas, S. R., Lanham-New, S. A., Wong, W. H. S., Ho, M. H. K., & Darling, A. L. (2019). Vitamin D Deficiency and Effects of Vitamin D Supplementation on Disease Severity in Patients with Atopic Dermatitis: A Systematic Review and Meta-Analysis in Adults and Children. Nutrients, 11(8), 1854. https://www.mdpi.com/2072-6643/11/8/1854
Hidayati, A. N., Sawitri, S., Sari, D. W., Prakoeswa, C. R. S., Indramaya, D. M., Damayanti, D., ... & Kusumaningrum, N. (2023). Efficacy of vitamin D supplementation on the severity of atopic dermatitis in children: A systematic review and meta-analysis. F1000Research. https://f1000research.com/articles/11-274
Huang, J., Zeng, Y., & Yuan, Y. (2024). Causal role of vitamin E in atopic dermatitis risk: A Mendelian randomization study. Food Science & Nutrition. https://onlinelibrary.wiley.com/doi/abs/10.1002/fsn3.4147
Huang, Y. Y., Liang, Y. T., Wu, J. M., Wu, W. T., Liu, X. T., Ye, T. T., ... & Chen, Y. P. (2023). Advances in the Study of Probiotics for Immunomodulation and Intervention in Food Allergy. Molecules, 28(3), 1242. https://www.mdpi.com/1420-3049/28/3/1242
Jaffary, F., Faghihi, G., Mokhtarian, A., & Hosseini, S. M. (2015). Effects of oral vitamin E on treatment of atopic dermatitis: A randomized controlled trial. Journal of Research in Medical Sciences, 20(11), 1053. https://journals.lww.com/jrms/fulltext/2015/20110/effects_of_oral_vitamin_e_on_treatment_of_atopic.5.aspx
Jiang, W., Ni, B., Liu, Z., Liu, X., Xie, W., Wu, I. X. Y., ... & Wong, V. C. H. (2020). The Role of Probiotics in the Prevention and Treatment of Atopic Dermatitis in Children: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. Pediatric Drugs, 22(5), 535-549. https://doi.org/10.1007/s40272-020-00410-6
Joshi, M., Hiremath, P., John, J., Ranadive, N., Nandakumar, K., & Mudgal, J. (2023). Modulatory role of vitamins A, B3, C, D, and E on skin health, immunity, microbiome, and diseases. Pharmacological Reports, 75(5), 1096-1114. https://doi.org/10.1007/s43440-023-00520-1
Kanda, N., Hoashi, T., & Saeki, H. (2021). Nutrition and Atopic Dermatitis. Journal of Nippon Medical School, 88(3), 171-177. https://www.jstage.jst.go.jp/article/jnms/88/3/88_JNMS.2021_88-317/_article/-char/ja/
Kiecka, A., Macura, B., & Szczepanik, M. (2023). Modulation of allergic contact dermatitis via gut microbiota modified by diet, vitamins, probiotics, prebiotics, and antibiotics. Pharmacological Reports, 75(2), 236-248. https://doi.org/10.1007/s43440-023-00454-8
Koh, L. F., Ong, R. Y., & Common, J. E. (2022). Skin microbiome of atopic dermatitis. Allergology International, 71(1), 31-39.
Koo, K., Nagayah, R., Begum, S., Tuan Mahmood, T. M., & Mohamed Shah, N. (2020). The use of complementary and alternative medicine in children with atopic eczema at a tertiary care centre in Malaysia. Complementary Therapies in Medicine, 49, 102355. https://www.sciencedirect.com/science/article/pii/S0965229919315511
Langan, S. M., Irvine, A. D., & Weidinger, S. (2020). Atopic dermatitis. The Lancet, 396(10247), 345-360. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31286-1/abstract
Li, Q., Zhou, Q., Zhang, G., Tian, X., Li, Y., Wang, Z., ... & Liu, Y. (2022). Vitamin D Supplementation and Allergic Diseases during Childhood: A Systematic Review and Meta-Analysis. Nutrients, 14(19), 3947. https://www.mdpi.com/2072-6643/14/19/3947
Li, Y., Zhang, B., Guo, J., Cao, Z., & Shen, M. (2022). The efficacy of probiotics supplementation for the treatment of atopic dermatitis in adults: a systematic review and meta-analysis. Journal of Dermatological Treatment, 33(6), 2800-2809. https://doi.org/10.1080/09546634.2022.2080170
Liu, Y., Du, X., Zhai, S., Tang, X., Liu, C., & Li, W. (2022). Gut microbiota and atopic dermatitis in children: a scoping review. BMC Pediatrics, 22(1), 323. https://doi.org/10.1186/s12887-022-03390-3
Mansour, N. O., Mohamed, A. A., Hussein, M., Eldemiry, E., Daifalla, A., Hassanin, S., ... & Elghobashy, N. (2020). The impact of vitamin D supplementation as an adjuvant therapy on clinical outcomes in patients with severe atopic dermatitis: A randomized controlled trial. Pharmacology Research & Perspectives, 8(6), e00679. https://onlinelibrary.wiley.com/doi/abs/10.1002/prp2.679
Moniaga, C. S., Tominaga, M., & Takamori, K. (2022). An Altered Skin and Gut Microbiota Are Involved in the Modulation of Itch in Atopic Dermatitis. Cells, 11(23), 3930. https://www.mdpi.com/2073-4409/11/23/3930
Navarro-López, V., Núñez-Delegido, E., Ruzafa-Costas, B., Sánchez-Pellicer, P., Agüera-Santos, J., & Navarro-Moratalla, L. (2021). Probiotics in the Therapeutic Arsenal of Dermatologists. Microorganisms, 9(7), 1513. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8303240
Park, J. S., Kim, M., Sol, I. S., Lee, K. S., Park, S., Yang, H. J., ... & Suh, D. I. (2022). Effect of Vitamin D on the Treatment of Atopic Dermatitis With Consideration of Heterogeneities: Meta-Analysis of Randomized Controlled Trials. Allergy, Asthma & Immunology Research, 15(2), 262-270. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10079516/
Puar, N., Chovatiya, R., & Paller, A. S. (2021). New treatments in atopic dermatitis. Annals of Allergy, Asthma & Immunology, 126(1), 21-31. https://www.sciencedirect.com/science/article/pii/S108112062030572X
Rajab, F. (2022). Holistic Treatment for the Management of Atopic Dermatitis. Dermatology Times, 43. https://www.dermatologytimes.com/view/holistic-treatment-for-the-management-of-atopic-dermatiti
Rodarte-Acosta, J. S., & Morales-Sánchez, M. A. (n.d.). El rol de la microbiota intestinal en la dermatitis atópica.
Siegels, D., Heratizadeh, A., Abraham, S., Binnmyr, J., Brockow, K., Irvine, A. D., ... & Worm, M. (2021). Systemic treatments in the management of atopic dermatitis: A systematic review and meta-analysis. Allergy, 76(4), 1053-1076. https://onlinelibrary.wiley.com/doi/abs/10.1111/all.14631
Sodré, C. S., Vieira, M. S., Estefan, J. L., Moraes, C., Cavalcante, F. S., dos Santos, K. R. N., ... & Pinto, L. A. M. (2022). The effect of probiotics on the clinical status of adult patients with atopic dermatitis: a systematic review. European Journal of Medical Research, 27(1), 94. https://doi.org/10.1186/s40001-022-00713-z
Tanojo, N., Citrashanty, I., Utomo, B., Listiawan, Y., Erviant, E., & Sawitri, D. (2023). Oral postbiotics derived from Lactobacillus sp. in treatment of atopic dermatitis: a meta-analysis. Acta Dermatovenerologica Alpina Pannonica et Adriatica, 32, 41-47.
Teo, C. W. L., Tay, S. H. Y., Tey, H. L., Ung, Y. W., & Yap, W. N. (2020). Vitamin E in Atopic Dermatitis: From Preclinical to Clinical Studies. Dermatology, 237(4), 553-564. https://doi.org/10.1159/000510653
Trikamjee, T., Comberiati, P., D'Auria, E., Peroni, D., & Zuccotti, G. V. (2021). Nutritional Factors in the Prevention of Atopic Dermatitis in Children. Frontiers in Pediatrics, 8, 577413. https://www.frontiersin.org/articles/10.3389/fped.2020.577413
Umborowati, M. A., Damayanti, D., Anggraeni, S., Endaryanto, A., Surono, I. S., Effendy, I., ... & Prakoeswa, C. R. S. (2022). The role of probiotics in the treatment of adult atopic dermatitis: a meta-analysis of randomized controlled trials. Journal of Health, Population and Nutrition, 41(1), 37. https://doi.org/10.1186/s41043-022-00318-6
Verduci, E., & Drago, L. (2020). Probiotics in the prevention and treatment of atopic dermatitis. IRIS. https://air.unimi.it/handle/2434/812262
Wegh, C. A. M., Geerlings, S. Y., Knol, J., Roeselers, G., & Belzer, C. (2019). Postbiotics and Their Potential Applications in Early Life Nutrition and Beyond. International Journal of Molecular Sciences, 20(19), 4673. https://www.mdpi.com/1422-0067/20/19/4673
DOI: https://doi.org/10.23857/pc.v9i9.7954
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